title: Comorbidities in young adults with vertebrogenic pathology and dysplastic phenotype
metadata.name: dc.contributor.author
metadata.value: Tibekina, Lyudmila M.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Spiricheva, Ekaterina V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Subbotina, Olga P.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2021-12-15T13:09:40Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2021-12-15T13:09:40Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2021-06
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Tibekina L. M., Spiricheva E. V., Subbotina O. P. Comorbidities in young adults with vertebrogenic pathology and dysplastic phenotype. Vestnik of Saint Petersburg University. Medicine, 2021, vol. 16, issue 2, pp. 95–105.
metadata.lang: en_GB
metadata.name: dc.identifier.other
metadata.value: https://doi.org/10.21638/spbu11.2021.203
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/33945
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: Pathological changes in the spine are often accompanied by pain syndrome at a young age.
  However, the significance of comorbid disorders in the formation and course of vertebrogenic
  pain syndrome has not been studied enough.The objective of the article to clarify the role of
  comorbid disorders in young adults with unclassified dysplastic phenotype in the formation
  of vertebrogenic pain syndrome. 61 male patients from 18 to 26 years old with pain syndrome
  in the spine were examined. Depending on the presence of signs of a dysplastic phenotype
  the patients were divided into two groups. The first group included 28 patients (median age
  22 (21; 23) years), the second group consisted of 33 people (median age 23 (19; 24) years). All
  patients underwent a comprehensive examination, including neurological and somatic examination,
  neuroradiological, ultrasound and psychological methods of investigation, also took
  into account clinical and anamnestic data. Pain syndrome, the state of the autonomic nervous
  system and the presence of signs of a dysplastic phenotype were assessed using scales and
  indices. Statistical data processing was performed using the STATISTICA 10.0 program. Differences
  were considered statistically significant when p < 0.05. According to neuroimaging
  data, signs of widespread dysplastic and more pronounced scoliotic and kyphoscoliotic
  changes of the spine, vertebral anomalies, segmental instability were authentically more frequent
  in patients with the unclassified connective tissue dysplasia phenotype (p<0,05). They
  had more severe vertebrogenic pain syndrome, which was more intense and long-lasting and
  was on the background of a greater neurological deficit with autonomic lability and psychopathological
  disorders, headaches, somatic dysfunction with a prevalence of diseases of the
  bronchopulmonary system and ENT organs in the control group (p<0.05). Research findings
  allow us to consider the prevalence of pathological changes in the spine, depressive disorders,
  somatic and cerebral burden as factors contributing to the formation of pain syndrome in
  patients with vertebrogenic pathology and connective tissue insufficiency.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: en
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Vestnik of St Petersburg University. Medicine;Volume 16; Issue 2
metadata.lang: -
metadata.name: dc.subject
metadata.value: young age
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: pain syndrome
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: comorbid diseases
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: connective tissue dysplasia
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: spine
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Comorbidities in young adults with vertebrogenic pathology and dysplastic phenotype
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 95-105.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/33945/1/95-105.pdf
resources.format: Adobe PDF
resources.size: 1,16 MB