title: Quality of life and muscle strength improvement in an amyotrophic lateral sclerosis patient after nutraceuticals
metadata.name: dc.contributor.author
metadata.value: de Carvalho, Jozélio Freire
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Yamasita, João Ricardo
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Churilov, Leonid P.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2021-03-12T15:48:18Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2021-03-12T15:48:18Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2020-09
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: de Carvalho J. F., Yamasita J. R., Churilov L. P. Quality of life and muscle strength improvement in an amyotrophic lateral sclerosis patient after nutraceuticals.Vestnik of Saint Petersburg University. Medicine, 2020, vol. 15, issue 3, pp. 221–227.
metadata.lang: en_GB
metadata.name: dc.identifier.other
metadata.value: https://doi.org/10.21638/spbu11.2020.308
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/25429
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: The objective of the article was to describe a patient with amyotrophic lateral sclerosis (ALS)
  treated with nutraceuticals who had a better quality of life and improved muscle strength. A
  65-year-old male patient with a past medical history of gout was diagnosed with amyotrophic
  lateral sclerosis in 2016. He received intravenous immunoglobulin and prednisone, but no
  improvement was observed. In 2018, he was diagnosed with multiple myeloma, submitted
  to a bone marrow transplant, and initiated riluzole. After 2 months, he came to our private
  clinic; he could not walk anymore and used outpatient nasal ventilator equipment. Beck anxiety
  inventory (BAI) was 20 [normal range (nr): < 8], Beck depression inventory (BDI) was
  12 (nr: < 10), Bristol stool form scale (BSTS) was 5 (nr: 3–4), and there were 7 symptoms of
  dysbiosis. Analogic visual scale (Lickert scale) for well-being was 5.0. We suspended the colchicine,
  added vitamin D3, creatine, vitamin C, N-acetyl cysteine, 5-hydroxytryptamine, B1,
  and B6 vitamins. Dysbiosis was also treated. After 2 months, he returned feeling much better,
  BAI and BDI reduced BDI to 11, and BSFS normalized. Following this evaluation, a nutraceutical
  prescription was added: methylfolate, zinc, magnesium, green tea extract, Ginkgo
  biloba, lipoic acid, pyrroloquinoline quinone, vitamin E, coenzyme Q10, and resveratrol. After 7 months, he was feeling very well; BAI and BDI were normal, he gained weight. He felt a
  marked improvement in his muscle strength, and he gained again the capacity of eating alone,
  his quality of life improved, and AVS well-being was 8.0. This report illustrates a demonstrative
  case of a patient with ALS treated with nutraceuticals and improved his quality of life and
  muscle strength. It may be an alternative therapeutic option for such patients.
metadata.lang: en_GB
metadata.name: dc.description.sponsorship
metadata.value: A contribution of L. P. Churilov was supported by the grant of the Government of Russian Federation
  for state support of scientific research carried out under the supervision of leading scientists, agreement
  14.W03.31.0009.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: en
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Vestnik of St Petersburg University. Medicine;Volume 15; Issue 3
metadata.lang: -
metadata.name: dc.subject
metadata.value: amyotrophic lateral sclerosis
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: neurological disorders
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: lower neuron disease
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: immunity
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: vitamin D
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: nutraceuticals
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: supplements
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Quality of life and muscle strength improvement in an amyotrophic lateral sclerosis patient after nutraceuticals
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 9964-Article Text-30745-1-10-20210223.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/25429/1/9964-Article%20Text-30745-1-10-20210223.pdf
resources.format: Adobe PDF
resources.size: 621,09 kB