title: Conformational and phase transitions in DNA - Photosensitive surfactant solutions: Experiment and modeling
metadata.name: dc.contributor.author
metadata.value: Kasyanenko, N
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Lysyakova, L
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Ramazanov, R
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Nesterenko, A
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Yaroshevich, I
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Titov, E
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Alexeev, G
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Lezov, A
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Unksov, I
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2016-04-08T09:46:11Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2016-04-08T09:46:11Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2015-02-01
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/1990
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: DNA binding to trans- and cis-isomers of azobenzene containing cationic surfactant in 5 mM NaCl solution was investigated by the methods of dynamic light scattering (DLS), low-gradient viscometry (LGV), atomic force microscopy (AFM), circular dichroism (CD), gel electrophoresis (GE), flow birefringence (FB), UV–Vis spectrophotometry. Light-responsive conformational transitions of DNA in complex with photosensitive surfactant, changes in DNA optical anisotropy and persistent length, phase transition of DNA into nanoparticles induced by high surfactant concentration, as well as transformation of surfactant conformation under its binding to macromolecule were studied. Computer simulations of micelles formation for cis- and trans-isomers of azobenzene containing surfactant, as well as DNA-surfactant interaction, were carried out. Phase diagram for DNA-surfactant solutions was designed. The possibility to reverse the DNA packaging induced by surfactant binding with the dilution and light irradiation was shown. © 2014 Wiley Periodicals, Inc. Biopolymers 103: 109–122, 2015.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: en
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: Biopolymers
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Volume 103, Issue 2, pages 109–122,;
metadata.lang: -
metadata.name: dc.subject
metadata.value: DNA-surfactant complexes
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: light-induced DNA de-compaction
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: phase diagram
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: DNA volume and persistent length
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Conformational and phase transitions in DNA - Photosensitive surfactant solutions: Experiment and modeling
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: Kasyanenko-.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/1990/1/Kasyanenko-.pdf
resources.format: Adobe PDF
resources.size: 155,72 kB