title: The effects of gene polymorphisms of the serotonin- and dopaminergic systems on the level of cognitive and neural functions in extreme conditions of professional activity
metadata.name: dc.contributor.author
metadata.value: Pyatibrat, Aleksandr O.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Melnov, Sergei B.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Balakhonov, Aleksey V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Kozlova, Anna S.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Pyatibrat, Elena D.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Shabanov, Peter D.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2016-08-02T09:08:20Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2016-08-02T09:08:20Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2016-03
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/2508
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: To assess changes in neurodynamic and cognitive functions associated with extreme exercise loads
  depending on gene polymorphism which regulates cerebral monoamic system, military men were examined. It is shown that the most informative techniques to assess changes in cognitive functions are
  “Arithmetic count” and “Conformity establishment”. The results of the examination stated that people
  with COMT Val/Val genotypes demonstrated evidently higher cognitive flexibility after extreme exercise
  loads at performing combat training tasks than those with alleles COMT Met. The most reliable
  results of changes in neurodynamic functions were obtained using techniques “Reaction to the moving
  object” and “Landolt’s rings visual acuity test”. Military men with genotypes 5HTT S/S, 5HT2A C/C
  and DRD2 A1/A1 demonstrated the best indices after extreme exercise loads than those with alleles
  5HTT L, 5HT2A T, DRD2 A2. Using methods of genetic screening allows a significant increase of
  prognostic selection and evaluation of specialists’ abilities necessary for the efficient activity in extreme
  conditions within the stated above forces. It was shown that gene analysis 5HTT, 5HT2A, DRD2 and
  COMT is significant at professional selection of the candidates to use difficult ergonomic systems at
  performing combat tasks.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: ru
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Vestnik of St Petersburg University. Series 11. Medicine;Issue 1
metadata.lang: -
metadata.name: dc.subject
metadata.value: military
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: extreme activity
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: gene polymorphism
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: molecular genetics
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: physical endurance
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: current mental state
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: cognitive function
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: neural function
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: The effects of gene polymorphisms of the serotonin- and dopaminergic systems on the level of cognitive and neural functions in extreme conditions of professional activity
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: Пятибрат_Мельнов_Балахонов_и_др.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/2508/1/%d0%9f%d1%8f%d1%82%d0%b8%d0%b1%d1%80%d0%b0%d1%82_%d0%9c%d0%b5%d0%bb%d1%8c%d0%bd%d0%be%d0%b2_%d0%91%d0%b0%d0%bb%d0%b0%d1%85%d0%be%d0%bd%d0%be%d0%b2_%d0%b8_%d0%b4%d1%80.pdf
resources.format: Adobe PDF
resources.size: 162,54 kB