title: Influence of antimicrobial substances of plant origin on the sensitivity of bacterial biofilm to antimicrobial drugs
metadata.name: dc.contributor.author
metadata.value: Rybalchenko, Oksana V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Orlova, Olga G.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Netesa, Maria A.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Kapustina, Valentina V.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2023-10-10T14:03:29Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2023-10-10T14:03:29Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2023-06
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Rybalchenko O. V., Orlova O. G., Netesa M. A., Kapustina V. V. Influence of antimicrobial substances of plant origin on the sensitivity of bacterial biofilm to antimicrobial drugs. Vestnik of Saint Petersburg University. Medicine, 2023, vol. 18, issue 2, pp. 176–191. https://doi.org/10.21638/spbu11.2023.206 (In Russian)
metadata.lang: en_GB
metadata.name: dc.identifier.other
metadata.value: https://doi.org/10.21638/spbu11.2023.206
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/44205
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: The widespread antibiotic resistance is associated with the formation of special forms of
  microbial communities — bacterial biofilms with increased resistance to the impact of various
  physicochemical factors, including antimicrobial drugs. In this regard, the investigation of
  antibacterial agents, including herbal preparations that could affect bacterial biofilms, seems
  to be of current interest. The aim of this work was to identify antibacterial substances of plant
  origin that can most effectively affect bacterial biofilms. The effect of antibacterial decoctions
  of lingonberry, sage, and chamomile plants on the sensitivity of bacteria to antimicrobial
  drugs was assessed. The susceptibility of bacteria to antimicrobial drugs, when combined with
  herbal decoctions, was determined by the disk-diffusion method. The morphophysiological
  properties of biofilms were illustrated by light and scanning electron microscopy. The ability
  of lingonberry, sage, and chamomile decoctions to increase the sensitivity of bacteria to
  antimicrobial drugs of predominantly bactericidal pharmacological action was revealed.
  Decoctions of medicinal plants prevented the formation of complete bacterial biofilms.
  The obtained results indicate the antibiofilm activity of lingonberry, chamomile and sage
  decoctions, which contribute to a decrease in the level of antibiotic resistance of bacteria and
  a decrease in the load during antimicrobial therapy.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: ru
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Vestnik of St Petersburg University. Medicine;Volume 18; Issue 2
metadata.lang: -
metadata.name: dc.subject
metadata.value: antibiotic resistance
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: antimicrobial drugs
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: bacterial biofilms
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: herbal decoctions
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Influence of antimicrobial substances of plant origin on the sensitivity of bacterial biofilm to antimicrobial drugs
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 06.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/44205/1/06.pdf
resources.format: Adobe PDF
resources.size: 869,15 kB