title: Influence of reproductively significant autoantibodies on the quality of oocytes, obtained embryos and the chances of implantation in Assisted Reproductive Technologies cycles. Literature review
metadata.name: dc.contributor.author
metadata.value: Safarian, Galina Kh.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Gzgzyan, Alexandr M.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Dzhemlikhanova, Lyailya Kh.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Niauri, Darico A.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Znobishina, Alexandra V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Borodina, Yelena S.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Nguyen, Cong Tuan
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2021-03-12T16:24:05Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2021-03-12T16:24:05Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2020-12
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Safarian G. Kh., Gzgzyan A. M., Dzhemlikhanova L. Kh., Niauri D. A., Znobishina A. V., Borodina Ye. S., Nguyen T. C. Influence of reproductively significant autoantibodies on the quality of oocytes, obtained embryos and the chances of implantation in Assisted Reproductive Technologies cycles. Literature review. Vestnik of Saint Petersburg University. Medicine, 2020, vol. 15, issue 4, pp. 256–273.
metadata.lang: en_GB
metadata.name: dc.identifier.other
metadata.value: https://doi.org/10.21638/spbu11.2020.404
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/25434
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: There is evidence suggesting that autoimmune mechanisms may influence fertility, manifesting
  as infertility or pregnancy loss. Numerous autoimmune diseases, including but not limited
  to systemic lupus erythematosus, anti-phospholipid syndrome and Hashimoto thyroiditis
  may be associated with infertility and pregnancy loss through different putative mechanisms.
  It is notable that fertility may be impaired in the presence of serum autoantibodies regardless
  of the presence of a clinically overt autoimmune disease. Autoimmunity may affect all stages
  of fertility via ovarian failure, implantation failure, and pregnancy loss. This review article will
  illustrate and discuss the available data on the link between chances of achieving pregnancy
  through Assisted Reproductive Technologies in real clinical setting in the presence of several
  autoantibodies affecting female reproductive system. Summarizing the available data from the
  world literature, it can be concluded that necessity exist in development of a reproductively
  significant antibodies line in application to direct, cross-over and cumulative assessment of
  the role of autoimmune antibodies carriage in the implementation of reproductive failures, bearing in mind new approaches to the strategy of overcoming autoimmune reproductive
  failure.
metadata.lang: en_GB
metadata.name: dc.description.sponsorship
metadata.value: The work is supported by a grant from the Government of the Russian Federation (contract
  14.W03.31.0009 of 13.02.2017) for state support of scientific research conducted under the supervision of
  leading scientists.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: en
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Vestnik of St Petersburg University. Medicine;Volume 15; Issue 4
metadata.lang: -
metadata.name: dc.subject
metadata.value: autoantibodies
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: TPO
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: APA
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: ANA
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: α-enolase
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: laminin-1
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: Se-binding protein 1
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Influence of reproductively significant autoantibodies on the quality of oocytes, obtained embryos and the chances of implantation in Assisted Reproductive Technologies cycles. Literature review
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 256-273.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/25434/1/256-273.pdf
resources.format: Adobe PDF
resources.size: 644,05 kB