title: Comparison of the specificity of ultra-violet and X-rays action on mutability of yeast
metadata.name: dc.contributor.author
metadata.value: Inge-Vechtomov, S.G.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Kožin, S.A.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Инге-Вечтомов, С.Г.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Кожин, С.А.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2018-01-16T12:49:35Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2018-01-16T12:49:35Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 1964
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Инге-Вечтомов С.Г., Кожин С.А. Сравнение специфичности действия ультрафиолетовых и рентгеновых лучей на мутабильность дрожжей // Исследования по генетике. 1964. Вып. 2, с. 77-85
metadata.lang: en_GB
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/8855
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: Red adenineless mutants have been induced in haploid of Saccharomyces cerevisiae by UV- and X-rays. 180 such mutants have proved to be distributed between two loci designed as adᵢ and adz. The adz locus have proved to be more sensitive to mutagenic action of both kinds of radiation than the adᵢ locus. Leaky and nonleaky mutants have been scored in both loci. In adᵢ locus we have considered alleles suppressible and nonsuppressible by the external dominant suppressor.
  Gene specificity of UV- and X-rays was determined by the ratio (adz mutations / adᵢ mutations). The gene specificity of these two agents appeared to be the same. Intragenic specificity of the mutagens used proved to be the same too. The latter kind of specificity was determined by the ratio (leaky mutations / nonleaky mutations ) both in adᵢ and the adz locus and by ratio ( suppressible mutations /
  nonsuppressible mutations) in the adᵢ locus.
  The cause of the different sensitivity to radiation of the loci under consideration is discussed. Two alternative hypotheses have been proposed to explain the impossibility to distinguish UV- and X-rays effects by means of observation of their mutagenic specificity:
  1) indirect action of the mutagens used;
  2) only one class of mutations, common for both mutagens, was scored. These are the point mutations. Chromosome aberrations by which the effect of UV- and X-rays distinguishable are supposed to be inviable.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: ru
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Исследования по генетике;
metadata.lang: -
metadata.name: dc.subject
metadata.value: ultra-violet
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: X-rays
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: yeast
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: mutations
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Comparison of the specificity of ultra-violet and X-rays action on mutability of yeast
metadata.lang: en_GB
metadata.name: dc.title.alternative
metadata.value: Сравнение специфичности действия ультрафиолетовых и рентгеновых лучей на мутабильность дрожжей
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 77_Inge_Kozin.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/8855/1/77_Inge_Kozin.pdf
resources.format: Adobe PDF
resources.size: 432,95 kB