title: On the nature of streptomycin-resistance in Chlorella
metadata.name: dc.contributor.author
metadata.value: Tugarinov, V.V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Tchruni, F.N.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Kvitko, K.V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Тугаринов, В.В.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Тхруни, Ф.Н.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Квитко, К.В.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2018-01-20T07:43:12Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2018-01-20T07:43:12Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 1971
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Тугаринов В.В., Тхруни Ф.Н., Квитко К.В. О природе стрептомицинустойчивости у хлореллы // Исследования по генетике. 1971. Вып. 4, с. 142-148
metadata.lang: en_GB
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/8894
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: As it was shown in previous publication, the streptomycin resistant to 500 units/ml mutations (sr-500) arise in clones of Chlorella only on solid media with streptomycin and therefore we regard them as non-preadaptive. Now we try to investigate the nature of sr-500 mutations by growing colonies before fluctuation test on a media with low streptomycin concentration and by testing bigger colonies.
  Cultivation of sensitive cells (ss) of Chlorella vulgaris (strain B) on low selecting dose of streptomycin (20 unitslml) led to the discovery of preadaptive clones, resistant to 500 unitslml.
  The fluctuation analysis of big clones of sensitive cells can reveal the infrequent cases of preadaptation to streptomycin.
  Heterogeneity of clones of resistant mutants is a indirect indication on a multistage process of adaptation to streptomycin.
  The adaptation of Chlorella cells to streptomycin could be considered as the results of selection and mutations in presence of the inhibitor.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: ru
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Исследования по генетике;
metadata.lang: -
metadata.name: dc.subject
metadata.value: CHLORELLA
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: mutations
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: streptomycin
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: On the nature of streptomycin-resistance in Chlorella
metadata.lang: en_GB
metadata.name: dc.title.alternative
metadata.value: О природе стрептомицинустойчивости у хлореллы
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 142_Tugarinov_Thruni_Kvitko.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/8894/1/142_Tugarinov_Thruni_Kvitko.pdf
resources.format: Adobe PDF
resources.size: 388,26 kB