title: Clinical Trials of Rhodiola rosea in Tomsk in the Late Soviet Period
metadata.name: dc.contributor.author
metadata.value: Vasilyev, Pavel A.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Zvonareva, Olga I.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Petrenko, Alexander N.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2020-10-19T17:01:52Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2020-10-19T17:01:52Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2020-09
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Vasilyev P.A., Zvonareva O.I., Petrenko A.N. Clinical Trials of Rhodiola rosea in Tomsk in the Late Soviet Period. Vestnik of Saint Petersburg University. History, 2020, vol. 65, issue 3, рp. 814– 825.
metadata.lang: en_GB
metadata.name: dc.identifier.other
metadata.value: https://doi.org/10.21638/11701/spbu02.2020.307
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/19926
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: Rhodiola rosea is a Siberian medicinal plant possessing qualities of a central nervous system
  stimulant that has been traditionally used in the folk medicine of the indigenous peoples in
  Siberia. Between the 1960s and the 1980s, the plant had been intensively studied in the scientific laboratories of Tomsk. The study of physicochemical properties of the plant and its effects
  on humans was initially carried out in the Tomsk Medical Institute (TMI) by a large research
  group headed by A. S. Saratikov and E.A.Krasnov. Following a series of animal studies in the
  early 1960s, Saratikov started to enlist human volunteers from TMI students and stuff and
  examine the effects of the plant on concentration and auto-suggestion. These trials were later
  expanded, and a number of medical institutions in Tomsk incorporated them into their research programs, seemingly hailing Rhodiola rosea as a potential all-curing miracle drug for
  the overworked and stressed modern self. (Interestingly enough, there has recently been a renewed interest in the plant in the West that has corroborated a number of Soviet findings). At
  the same time, research into the history of Rhodiola rosea trials also highlights both numerous
  ethically problematic issues in the treatment of research participants as well as unexpected
  divergences from the officially prescribed Soviet clinical trials practices. Using examples from
  a large number of published scientific studies and corroborating them with materials from oral history interviews with researchers and study participants, this paper explores the local
  idiosyncrasies that shaped Soviet clinical trials on the ground.
metadata.lang: en_GB
metadata.name: dc.description.sponsorship
metadata.value: Funded by the Russian Science Foundation (grant no. 18-78-10016, “Balancing knowledge reliability
  and ethical acceptability in clinical trials: from emergence of a randomized controlled trial to precision
  medicine”).
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: en
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Vestnik of St Petersburg University. History;Volume 65; Issue 3
metadata.lang: -
metadata.name: dc.subject
metadata.value: Rhodiola rosea
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: A. S. Saratikov
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: Tomsk pharmacological research school
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: History of medicine in Tomsk
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: Bioethics
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Clinical Trials of Rhodiola rosea in Tomsk in the Late Soviet Period
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 814-825.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/19926/1/814-825.pdf
resources.format: Adobe PDF
resources.size: 715,92 kB