title: Platelet functional activity in rats, prolonged experiencing regular exercise
metadata.name: dc.contributor.author
metadata.value: Medvedev, Ilya N.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2017-01-27T15:41:24Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2017-01-27T15:41:24Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2016-12
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Medvedev I. N. Platelet functional activity in rats, prolonged experiencing regular exercise. Vestnik SPbSU. Series 3. Biology, 2016, issue 4, pp. 99–107.
metadata.lang: en_GB
metadata.name: dc.identifier.other
metadata.value: 10.21638/11701/spbu03.2016.407
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/5977
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: Purpose — to fi nd out the possibility of long-term regular exercise restrain the increase in age-platelet
  activity in rats. The study included 26 healthy male rats 6 months age, experience during the 1.5 years
  of daily exercise. Control presented 124 healthy males dye-contained in the standard terms. In the
  control rats with increasing age there is a gradual increase in functional activity of platelets. Regular
  daily exercise in rats between 6 and 24 months life were able to stabilize the functional activity of
  platelets, inhibiting its gain with age. Physical activity in rats provided throughout the observation
  time preserving low number of places on the surface of the platelet thrombin inductor strong fixation.
  This was accompanied by a small stable activity of phospholipase C, containment diacylglycerol
  synthesis and protein kinase C with an inactive fosfolirirovaniem contractile proteins platelet system.
  A small amount of inositol triphosphate provided with slowing revenue Ca2+ from the depot of blood
  platelets, helping to reduce the severity of the preservation of actomyosin in close to its original level.
  Thus physical exercise provide inhibition of platelet aggregation with adenosine diphosphate indicating
  the fibrinogen receptor on platelets fiziologizatsiyu expression and activity of phospholipase A2 in
  them, allowing segregation of optimal amounts of arachidonic acid from membrane phospholipids.
  Refs 14. Table 1.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: ru
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Vestnik of St Petersburg University. Series 3. Biology;Issue 4
metadata.lang: -
metadata.name: dc.subject
metadata.value: platelet aggregation
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: ontogenesis
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: rats
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: physical activity
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Platelet functional activity in rats, prolonged experiencing regular exercise
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 07-Medvedev.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/5977/1/07-Medvedev.pdf
resources.format: Adobe PDF
resources.size: 133,42 kB