title: Fibroblast growth factor 21 and its influence on metabolic processes in the human body
metadata.name: dc.contributor.author
metadata.value: Proshchai, Galina A.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Vorokhobina, Natalia V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Zagarskikh, Elena Y.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Partsernyak, Sergey A.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Partsernyak, Alexander S.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2018-04-25T10:05:29Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2018-04-25T10:05:29Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2018-03
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Proshchai G. A., Vorokhobina N. V., Zagarskikh E. Y., Partsernyak S. A., Partsernyak A. S. Fibroblast growth factor 21 and its influence on metabolic processes in the human body. Vestnik of Saint Petersburg University. Medicine, 2018, vol. 13, issue 1, pp. 38–45.
metadata.lang: en_GB
metadata.name: dc.identifier.other
metadata.value: 10.21638/11701/spbu11.2018.104
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/9449
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: Fibroblast Growth Factor 21 (FGF21) regulates mainly glucose and lipid metabolism. It improves insulin sensitivity, increases high-density lipoprotein, decreases serum triglyceride, low-density lipoprotein, blood glucose level and body weight. However, high circulating FGF21 levels have been found in the case of the type 2 diabetes, chronic heart disease, non-alcoholic fatty liver disease, obesity and other. These findings may indicate the FGF21 resistance or compensatory response to the metabolic stress. Thus, serum FGF21 can be seen as a potential marker of these metabolic disorders. The purpose of this review has been to summarize the scientific date of influence FGF21 on the development of the diseases which associated with metabolic disorders.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: ru
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Vestnik of St Petersburg University. Medicine;Volume 13; Issue 1
metadata.lang: -
metadata.name: dc.subject
metadata.value: Fibroblast growth factor 21
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: 2nd Type Diabetes Mellitus
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: Cardiovascular disease
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: Insulin resistance
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: Obesity
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Fibroblast growth factor 21 and its influence on metabolic processes in the human body
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 04-Proshchay.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/9449/1/04-Proshchay.pdf
resources.format: Adobe PDF
resources.size: 630,28 kB