title: Auditory brainstem and cognitive evoked potentials in assessment of brain functional status in patients with ischemic stroke
metadata.name: dc.contributor.author
metadata.value: Boricheva, Daria O.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Tibekina, Liudmila M.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Aleksandrov, Aleksandr A.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2019-07-17T14:36:13Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2019-07-17T14:36:13Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2019-03
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Boricheva D. O., Tibekina L. M., Aleksandrov A. A. Auditory brainstem and cognitive evoked potentials in assessment of brain functional status in patients with ischemic stroke. Vestnik of Saint Petersburg University. Medicine, 2019, vol. 14, issue 1, pp. 25–34.
metadata.lang: en_GB
metadata.name: dc.identifier.other
metadata.value: https://doi.org/10.21638/11701/spbu10.2019.103
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/15966
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: Current research aimed to investigate informational content of brainstem acoustic evoked potentials (BAEPs) and auditory cognitive event-related potential — mismatch negativity (MMN) in assessment of brain functional status and cognitive functions in patients with ischemic stroke. MMN is a component of auditory event-related potential with peak latency at 100–250 ms, which reflects automatic process of difference detection between stimuli and neurodynamic processes in auditory cortex at pre-attentive stage. Clinical and neurophysiological examination, including registration of BAEPs and MMN was performed for 22 patients (12 — with ischemic stroke in carotid circulation, 10 — without cerebrovascular diseases). According to results obtained using scales of MMSE, FAB, test with 10 words repetition and Schulte tables, patients with IS demonstrated cognitive impairment as compared to control group. During BAEPs examination, functional changes in brainstem were observed (increased latency of wave V and elongation of interpeak intervals III-V on both sides and III–V ipsilaterally) in patients with ischemic stroke. Also they demonstrated increased peak latency and decreased amplitude of MMN. It points at a decline in auditory discrimination accuracy, shortened lifetime of memory traces and deficit in involuntary attention switching and also indicates of cognitive impairment.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: en
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Vestnik of St Petersburg University. Medicine;Volume 14; Issue 1
metadata.lang: -
metadata.name: dc.subject
metadata.value: ischemic stroke
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: cognitive impairment
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: mismatch negativity
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: acoustic brainstem evoked potentials
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: auditory evoked potentials
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Auditory brainstem and cognitive evoked potentials in assessment of brain functional status in patients with ischemic stroke
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 25-34.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/15966/1/25-34.pdf
resources.format: Adobe PDF
resources.size: 679,6 kB