title: Hemocyte proteome of the Lake Baikal endemic Eulimnogammarus verrucosus (Crustacea: Amphipoda) sheds light on immune-related proteins
metadata.name: dc.contributor.author
metadata.value: Zolotovskaya, Elena
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Nazarova, Anna
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Saranchina, Alexandra
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Mutin, Andrei
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Drozdova, Polina
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Lubyaga, Yulia
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Timofeyev, Maxim
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2022-01-12T12:43:09Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2022-01-12T12:43:09Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2021-12
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Zolotovskaya, E., Nazarova, A., Saranchina, A., Mutin, A., Drozdova, P., Lubyaga, Yu., and Timofeyev, M. 2021. Hemocyte proteome of the Lake Baikal endemic Eulimnogammarus verrucosus (Crustacea: Amphipoda) sheds light on immune-related proteins. Bio. Comm. 66(4): 290–301.
metadata.lang: en_GB
metadata.name: dc.identifier.other
metadata.value: https://doi.org/10.21638/ spbu03.2021.402
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/34130
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: Hemocytes are cells circulating in the hemolymph and playing an important role in crustacean immunity. These cells not only function as phagocytes but also express immune compounds to the hemolymph. Here we obtained hemocyte proteome of the endemic amphipod (Amphipoda, Crustacea) Eulimnogammarus verrucosus from Lake Baikal, the first hemocyte proteome of an amphipod, using liquid chromatography/tandem mass spectrometry (LC-MS/MS). A total of 1152 unique proteins were discovered with LC-MS/MS. We discovered both proteins directly involved in the immune response, such as pattern recognition proteins (C-type lectins), and compounds with antimicrobial activity (ctenidin and anti-lipopolysaccharide factor/scygonadin). Moreover, hemocyanins which may act as a phenoloxidase and C-type lectins were among the most diverse protein groups in the hemocyte proteome. The obtained data can be useful for further studies of immune components and mechanisms in Baikal amphipods.
metadata.lang: en_GB
metadata.name: dc.description.sponsorship
metadata.value: The reported study was funded
  by Russian Foundation for Basic Research
  and the Government of the Irkutsk Region,
  project No. 20-44-383007.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: en
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Biological Сommunications;Volume 66; Issue 4
metadata.lang: -
metadata.name: dc.subject
metadata.value: hemocytes
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: LC-MS/MS
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: proteome
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: Lake Baikal
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: crustacean
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: amphipod
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: innate immunity
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: antimicrobial peptide
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: lectin
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Hemocyte proteome of the Lake Baikal endemic Eulimnogammarus verrucosus (Crustacea: Amphipoda) sheds light on immune-related proteins
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 290-301.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/34130/1/290-301.pdf
resources.format: Adobe PDF
resources.size: 2,35 MB