title: Role of the oral microbiota in the development of Alzheimer’s disease
metadata.name: dc.contributor.author
metadata.value: Gavrilova, Natalia Yu.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Gladyshev, Nikita S.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Kotrova, Anna D.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Morosova, Anastasiia S.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Soprun, Lidiia A.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Volovnikova, Victoria A.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Fedotkina, Tamara V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Shishkin, Alexandr N.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2021-03-12T16:02:35Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2021-03-12T16:02:35Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2020-12
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Gavrilova N. Yu., Gladyshev N. S., Kotrova A. D., Morozova A. S., Soprun L. A., Volovnikova V. A., Fedotkina T. V., Shishkin A. N. Role of the oral microbiota in the development of Alzheimer’s disease. Vestnik of Saint Petersburg University. Medicine, 2020, vol. 15, issue 4, pp. 231–238.
metadata.lang: en_GB
metadata.name: dc.identifier.other
metadata.value: https://doi.org/10.21638/spbu11.2020.401
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/25431
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: Dementia and, in particular, Alzheimer’s disease (AD), affects millions of people around the
  world and its prevalence is steadily rising annually. Some risk factors for AD, such as age, cannot
  be modified, while others could possibly be corrected. In recent years, many studies are
  tackling the problem of the oral and gut microbiota as a provoking factor for AD and other
  neurodegenerative diseases, but their relationship and specific pathophysiological mechanisms
  remain understudied. The microbiota of the oral cavity can be of particular importance
  due to the specificity of microorganisms and their localization, as well as the possibility of
  provoking neuroinflammation, which requires further study. This review covers the specific
  features of the oral microbiota, current views on the pathophysiological role of the oral microbiota
  in the development of AD, as well as the beneficial role of probiotics. The study of this
  issue can have an important practical application both for the early diagnosis of AD, and for
  its further treatment.
metadata.lang: en_GB
metadata.name: dc.description.sponsorship
metadata.value: This work was supported by the grant from the Government of the Russian Federation (contract
  No. 14.W03.31.0009 dated February 13, 2017) on the allocation of the grant for the state support of scientific
  researches conducted under the guidance of leading scientists.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: en
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Vestnik of St Petersburg University. Medicine;Volume 15; Issue 4
metadata.lang: -
metadata.name: dc.subject
metadata.value: Alzheimer’s disease
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: oral cavity
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: microbiota
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: probiotics
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: neurodegenerative diseases
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Role of the oral microbiota in the development of Alzheimer’s disease
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 231-238.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/25431/1/231-238.pdf
resources.format: Adobe PDF
resources.size: 592,21 kB