title: The role of central nervous system in the regulation of cell division process and of radiosensitivity of chromosomes of corneal epithelial cells in mice
metadata.name: dc.contributor.author
metadata.value: Tsapygina, R.I.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Цапыгина, Р.И.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2018-01-19T10:43:46Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2018-01-19T10:43:46Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 1971
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Цапыгина Р.И. Роль центральной нервной системы в регуляции процессов клеточного деления и радиочувствительности хромосом клеток эпителия роговицы у мышей // Исследования по генетике. 1971. Вып. 4, с. 54-60
metadata.lang: en_GB
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/8888
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: It is well known that the influence of stress factors on mitosis occurs by means of reactive inhibition of the beginning of cell division. This inhibition is reflective in its nature.
  The role of central nervous system in the regulation of cell division process as well as radiosensitivity of chromosomes is considered in the article. The study is performed with the males of CC57W stock of mice using the method of conditioned reflex. The effect of each of combined stimuli (conditioned and unconditioned) has been studied and punishment stimulation has been included into stereotype.
  Both conditioned and unconditioned stimuli after the formation of conditioned reflex (after 63 combinations) determine significant decrease of mitotic index in corneal epithelium. Punishment stimulation (in 142 combinations) did not give such an effect.  Conditioned and unconditioned stimuli applied in two hours after irradiation of an experimental animal with X-rays (100 r) caused the decrease of the level of chromosomal aberrations in cells fixed in 24 hour after irradiation.
  It is suggested that cell division process and the formation of induced chromosomal aberrations are under control of central nervous system.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: ru
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Исследования по генетике;
metadata.lang: -
metadata.name: dc.subject
metadata.value: central nervous system
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: X-rays
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: cell division process
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: corneal epithelial
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: The role of central nervous system in the regulation of cell division process and of radiosensitivity of chromosomes of corneal epithelial cells in mice
metadata.lang: en_GB
metadata.name: dc.title.alternative
metadata.value: Роль центральной нервной системы в регуляции процессов клеточного деления и радиочувствительности хромосом клеток эпителия роговицы у мышей
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 54_Tsapygina.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/8888/1/54_Tsapygina.pdf
resources.format: Adobe PDF
resources.size: 607,45 kB