title: The pathogenesis of pulmonary hypertension — vessel wall ischemia as the driving force in disease initiation and progression
metadata.name: dc.contributor.author
metadata.value: Heise, Emma L.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Churilov, Leonid P.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Novitskaya, Tatiana A.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Yablonsky, Piotr K.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Haverich, Axel
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2021-08-25T10:21:07Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2021-08-25T10:21:07Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2021-03
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Heise E. L., Churilov L. P., Novitskaya T. A., Yablonsky P. K., Haverich A. The pathogenesis of pulmonary hypertension — vessel wall ischemia as the driving force in disease initiation and progression. Vestnik of Saint Petersburg University. Medicine, 2021, vol. 16, issue 1, pp. 20–36.
metadata.lang: en_GB
metadata.name: dc.identifier.other
metadata.value: https://doi.org/10.21638/spbu11.2021.103
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/32933
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: Surgeons are not trained to decipher the pathogenesis of diseases, which they operate on. They
  are used to repair, remove, or replace defective tissues and organs. Yet, we often see typical
  pathomorphological or pathophysiological phenomena, characteristic of a specific disorder
  that can only be observed during surgery. Such patterns would not be recognized easily by
  current imaging techniques, and their visibility would require a living organism. In modern
  terminology, one could call them “surgical biomarkers”. Many disease entities, today, are still
  not completely deciphered regarding initial links of their pathogenesis, despite decades of
  experimental and clinical research. In such disorders, characteristically named “idiopathic”,
  surgical observations may be helpful to clarify disease mechanisms, two of which we offer here
  for one of these disease entities, namely pulmonary hypertension.
metadata.lang: en_GB
metadata.name: dc.description.sponsorship
metadata.value: The work of L. P. Churilov and P. K. Yablonsky was supported by the grant of the Russian Federation
  Government, for state support of the research conducted under the guidance of leading scientists, contract
  14.W03.31.0009.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: en
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Vestnik of St Petersburg University. Medicine;Volume 16; Issue 1
metadata.lang: -
metadata.name: dc.subject
metadata.value: arteria pulmonalis
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: pulmonary hypertension
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: vasa vasorum
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: vasculitis
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: autoimmunity
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: atherosclerosis
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: The pathogenesis of pulmonary hypertension — vessel wall ischemia as the driving force in disease initiation and progression
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 20-36.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/32933/1/20-36.pdf
resources.format: Adobe PDF
resources.size: 2,5 MB