title: Cytostatic activity in the hydrophilic fraction of the crude extract from the White Sea sponge Halichondria panicea
metadata.name: dc.contributor.author
metadata.value: Khalaman, Vyacheslav
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Chalisova, Natalia
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Krasnov, Konstantin
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Alexandrova, Marina
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2019-06-26T20:03:58Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2019-06-26T20:03:58Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2019-03
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Khalaman, V., Chalisova, N., Krasnov, K., and Alexandrova, M. 2019. Cytostatic activity in the hydrophilic fraction of the crude extract from the White Sea sponge Halichondria panicea. Bio. Comm. 64(1): 41–45.
metadata.lang: en_GB
metadata.name: dc.identifier.other
metadata.value: https://doi.org/10.21638/ spbu03.2019.105
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/15790
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: Halichondria panicea, commonly known as the breadcrumb sponge, is an ecologically aggressive and widespread species in the coastal waters of North Atlantic and North Pacific. Cytostatic activity of the water-soluble extract fraction from the White Sea sponge Halichondria panicea was tested using organotypic cultures of rat liver fragments. The study shows a pronounced negative dose-dependent effect of the extract on the development of tissue explants of the test animals. Our results confirm toxicity of the White Sea Halichondria panicea, which was revealed earlier toward marine epibenthic organisms. The chemical nature of a substance or substances responsible for toxic effect is discussed.
metadata.lang: en_GB
metadata.name: dc.description.sponsorship
metadata.value: This work was supported by the Program of Division of Biological Sciences RAS (Reg. number АААА-А19-119022690122-5).
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: en
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Biological Communications;Volume 64; Issue 1
metadata.lang: -
metadata.name: dc.subject
metadata.value: Halichondria panicea
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: White Sea
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: organotypic culture
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: cytostatic activity
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: crude extract
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Cytostatic activity in the hydrophilic fraction of the crude extract from the White Sea sponge Halichondria panicea
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 2918-Article Text-10692-1-10-20190524.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/15790/1/2918-Article%20Text-10692-1-10-20190524.pdf
resources.format: Adobe PDF
resources.size: 201,38 kB