title: Molecular cytogenetic characterization of two murine cancer cell lines derived from salivary gland
metadata.name: dc.contributor.author
metadata.value: Steinacker, Ralf
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Liehr, Thomas
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Kosyakova, Nadezda
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Rincic, Martina
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Hussein Azawi, Shaymaa S.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2019-04-01T15:45:52Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2019-04-01T15:45:52Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2018-12
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Steinacker, R., Liehr, T., Kosyakova, N., Rincic, M., and Hussein Azawi, S. S. 2018. Molecular cytogenetic characterization of two murine cancer cell lines derived from salivary gland. Bio. Comm. 63(4): 243–255.
metadata.lang: en_GB
metadata.name: dc.identifier.other
metadata.value: 10.21638/spbu03.2018.403
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/15410
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: Here two murine salivary gland cancer (SGC) cell lines WR21 and SCA-9 were
  studied for the first time in detail by high-resolution molecular cytogenetic approaches.
  This study revealed that these cell lines are models for human SGCs
  of initial stage myoepithelioid or mucoepidermoid (WR21) and of advanced
  stage mucoepidermoid (SCA-9) tumors. Besides, three genes most likely playing
  a role in SGC development (FGF10, ELAVL1/HUR and SEL1) were identified.
  All of them were involved in translocation events in these in vitro models and
  thus were most likely activated. Overall, the present study highlights the necessity
  not only to establish but also to genetically characterize murine tumor cell
  lines. Without such a characterization they cannot be used in a reasonable way
  in research.
metadata.lang: en_GB
metadata.name: dc.description.sponsorship
metadata.value: This work was supported by Grant No. 2013.032.1 of the Wilhelm Sander‑Stiftung.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: en
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Biological Communications;Volume 63; Issue 4
metadata.lang: -
metadata.name: dc.subject
metadata.value: salivary gland cancer (SGC)
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: murine tumor cell lines
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: WR21
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: SCA-9
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: myoepithelioid SGC
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: mucoepidermoid SGC
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: FGF10
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: ELAVL1/HUR
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: SEL1
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Molecular cytogenetic characterization of two murine cancer cell lines derived from salivary gland
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 03-Steinacker.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/15410/1/03-Steinacker.pdf
resources.format: Adobe PDF
resources.size: 1,41 MB