title: Developing translational biological psychiatry: Learning from history to build the future
metadata.name: dc.contributor.author
metadata.value: Demin, Konstantin
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Meshalkina, Darya
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Lakstygal, Anton
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Kalueff, Allan
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2018-06-06T09:32:57Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2018-06-06T09:32:57Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2017-12
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Demin, K., Meshalkina, D., Lakstygal, A., and Kalueff, A. 2017. Developing translational biological psychiatry: Learning from history to build the future. Bio. Comm. 62(4): 278–292.
metadata.lang: en_GB
metadata.name: dc.identifier.other
metadata.value: 10.21638/11701/ spbu03.2017.407
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/10262
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: Psychiatric disorders are among the most complex human disorders that, albeit
  often difficult to diagnose and treat, are widespread in modern society.
  Biological psychiatry studies biological functions of the central nervous system
  as mental disorders develop. Today’s biological psychiatry is facing multiple
  conceptual problems that prevent our deeper understanding of disease pathogenesis
  and delay the invention of new treatments. Thus, providing a historical
  context to this rapidly developing field may help scientists better understand
  the existing challenges and their potential solutions. Here, we discuss the main
  conceptual problems and paradigms of biological psychiatry, including the lack
  of reproducibility and/or valid theories, through an historical overview of its
  role in addressing theoretical and clinical questions. We propose a wider use of
  the translational approach in psychiatry to expand our analyses of psychiatric
  disorders to other species, and as a tool to create and further develop theories
  and concepts in this field.
metadata.lang: en_GB
metadata.name: dc.description.sponsorship
metadata.value: This work was supported by the
  Russian Foundation for Basic Research
  (RFBR) Grant 16-04-00851.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: en
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Biological Communications;Volume 62; Issue 4
metadata.lang: -
metadata.name: dc.subject
metadata.value: biological psychiatry
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: translational medicine
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: history of psychiatry
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: modern psychiatry
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: conceptual issues in psychiatry
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Developing translational biological psychiatry: Learning from history to build the future
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 07-Demin.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/10262/1/07-Demin.pdf
resources.format: Adobe PDF
resources.size: 1,89 MB