title: Synthesis of α-keto-δ-(NG,NG–dimethylguanidino)valeric acid as a regulator of NO-synthetase activity
metadata.name: dc.contributor.advisor
metadata.value: Глуздиков Иван Александрович
metadata.lang: ru_RU
metadata.name: dc.contributor.author
metadata.value: Марченко Сергей Алексеевич
metadata.lang: ru_RU
metadata.name: dc.contributor.author
metadata.value: Marchenko Sergei
metadata.lang: en_GB
metadata.name: dc.contributor.editor
metadata.value: кандидат химических наук И.А. Глуздиков
metadata.lang: ru_RU
metadata.name: dc.contributor.editor
metadata.value: Candidate of Chemistry I.A. Gluzdikov
metadata.lang: en_GB
metadata.name: dc.date.accessioned
metadata.value: 2016-10-10T02:11:06Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2016-10-10T02:11:06Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2016
metadata.name: dc.identifier.other
metadata.value: 010108
metadata.lang: en_GB
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/3961
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: В работе были рассмотрены различные способы гуанилирования и  разработан препаративный метод синтеза α-кето-δ-(NG,NG-диметилгуанидино) валериановой кислоты (DMVG) в 11 стадий. Полученное соединение было очищено с помощью препаративной ВЭЖХ и идентифицировано методами масс и ЯМР спектроскопии.
metadata.lang: ru_RU
metadata.name: dc.description.abstract
metadata.value: In this work we considered different methods of guanilation and developed preparative method of synthesis of α-keto-δ-(NG,NG- dimethylguanidino) valeric acid (DMVG) in eleven-step. The obtained compound was purified by preparative HPLC and identified by mass and NMR spectroscopy.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: ru
metadata.name: dc.subject
metadata.value: DMVG
metadata.lang: ru_RU
metadata.name: dc.subject
metadata.value: ADMA
metadata.lang: ru_RU
metadata.name: dc.subject
metadata.value: тиоцитрулин
metadata.lang: ru_RU
metadata.name: dc.subject
metadata.value: ВЭЖХ
metadata.lang: ru_RU
metadata.name: dc.subject
metadata.value: DMVG
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: ADMA
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: thiocitruline
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: HPLC
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Synthesis of α-keto-δ-(NG,NG–dimethylguanidino)valeric acid as a regulator of NO-synthetase activity
metadata.lang: en_GB
metadata.name: dc.title.alternative
metadata.value: Синтез α-кето-δ-(NG,NG-диметилгуанидино)валериановой кислоты - регулятора активности NO-синтетазы
metadata.lang: ru_RU
resources.filename: diplomnaya_rabota_Marchenko_S_11.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/3961/1/diplomnaya_rabota_Marchenko_S_11.pdf
resources.format: Adobe PDF
resources.description: Article
resources.size: 1,44 MB
resources.filename: reviewSV_st003476_Gluzdikov_Ivan_Aleksandrovich_(supervisor)(En).txt
resources.url: https://dspace.spbu.ru/bitstream/11701/3961/2/reviewSV_st003476_Gluzdikov_Ivan_Aleksandrovich_%28supervisor%29%28En%29.txt
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resources.description: ReviewSV
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resources.filename: reviewSV_st003476_Gluzdikov_Ivan_Aleksandrovich_(supervisor)(Ru).txt
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resources.filename: reviewSV_st003476_Gluzdikov_Ivan_Aleksandrovich_(reviewer)(Ru).txt
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