title: The potentialities of enotherapy in the correction of experimental hypoxia’s effects
metadata.name: dc.contributor.author
metadata.value: Kubyshkin, Anatoliy V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Shramko, Yuliana I.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Aliev, Leonid L.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Beketov, Alexey A.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Ogai, Yury A.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Chernousova, Inna V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Fomochkina, Iryna I.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Tarimov, Cyril O.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2019-01-29T10:41:53Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2019-01-29T10:41:53Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2018-12
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Kubyshkin A. V., Shramko Yul. I., Aliev L. L., Beketov A. A., Ogai Yu. A., Chernousova I. V., Fomochkina I. I., Tarimov C. O. The potentialities of enotherapy in the correction of experimental hypoxia’s effects. Vestnik of Saint Petersburg University. Medicine, 2018, vol. 13, issue 4, pp. 366–375.
metadata.lang: en_GB
metadata.name: dc.identifier.other
metadata.value: 10.21638/11701/spbu11.2018.404
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/15352
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: The aim of the work was to study the influence of sparkling wines on the main markers of
  hypoxia. Material and methods. The experiment was carried out on 25 white male rats weighing 180–200 grams (age 10–12 weeks.). Animals of group 1 were control animals and received
  drinking water. Animals of the second group received water and were subjected to bloodletting
  on the 1st week. Animals of the 3rd group were subjected to bloodletting on the 1st week
  and received diluted sparkling wine as drinking water. Animals of group 4 were not subjected
  to bloodletting and received diluted sparkling wine as drinking water throughout the experiment.
  Sparkling wine was given at a dose of 300 ml of wine per 70 kg of body weight. In the
  blood serum, markers of free radical oxidation and markers of inflammation formed in hypoxic
  damage were studied. Results: the use of sparkling wines for correction of biochemical
  disorders in hypoxia led to the strengthening of antioxidant protection systems: the level of
  superoxide dismutase showed an increase of 77 % (p < 0,05) comparing to the group with simulated
  hypoxia, the growth of catalase activity by 5 times, the values of trypsin-like activity and
  elastase-like activity were lower than the hypoxic level by 20 % (p < 0,05) and 59 % (p < 0,01),
  respectively. Conclusion: the use of sparkling red wine in the correction of free-radical and
  proteolytic damage, typical for hypoxia, revealed a complex positive effect on a number of
  important indicators of antioxidant and antiproteolytic protection of the body. This indicates
  the prospects for further experimental and clinical studies in this direction.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: ru
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Vestnik of St Petersburg University. Medicine;Volume 13; Issue 4
metadata.lang: -
metadata.name: dc.subject
metadata.value: sparkling wines
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: hypoxia
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: free-radical oxidation
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: proteolysis
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: The potentialities of enotherapy in the correction of experimental hypoxia’s effects
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 04-Kubyshkin.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/15352/1/04-Kubyshkin.pdf
resources.format: Adobe PDF
resources.size: 622,3 kB