title: Comparative analysis of FTIR spectra of serum from multiple myeloma patients and healthy donors
metadata.name: dc.contributor.author
metadata.value: Plotnikova, Lyudmila V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Polyanichko, Alexander M.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Uspenskaya, Maya V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Garifullin, Andrew D.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Voloshin, Sergey V.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2017-07-04T15:27:31Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2017-07-04T15:27:31Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2017-03
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Plotnikova L. V., Polyanichko A. M., Uspenskaya M.V., Garifullin A. D., Voloshin S. V. Comparative analysis of FTIR spectra of serum from multiple myeloma patients and healthy donors. Vestnik SPbSU. Physics and Chemistry. 2017, vol. 4 (62), issue 1, pp. 34–40.
metadata.lang: en_GB
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/6653
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: Multiple myeloma (MM) accounts for about 1% of all types of cancers. MM is characterized by
  the proliferation of a single clone of plasma cells, which may produce and secrete homogeneous
  monoclonal immunoglobulin. The monoclonal immunoglobulin is commonly referred to as an “M-protein”. The M-protein acts as a serological “tumor” marker that is useful for diagnosis and
  disease monitoring. The electrophoretic pattern reveals the M-protein in 80% of MM patients as
  a single peak or localized band. In our study we applied a combination of high-resolution protein
  electrophoresis and Attenuated Total Reflection (ATR) infrared spectroscopy (FTIR) to compare
  the protein composition and the secondary structures of the serum proteins from MM patients
  and healthy donors. Refs 15. Figs 3. Tables 1.
metadata.lang: en_GB
metadata.name: dc.description.sponsorship
metadata.value: Работа поддержана Правительством Российской Федерации (грант 074-U01) и Российским фондом
  фундаментальных исследований (грант №15- 08-06876).
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: ru
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Vestnik of St Petersburg University. Physics and Chemistry;Volume 4 (62); Issue 1
metadata.lang: -
metadata.name: dc.subject
metadata.value: multiple myeloma
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: monoclonal immunoglobulin
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: secondary structure
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: IR-spectroscopy
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Comparative analysis of FTIR spectra of serum from multiple myeloma patients and healthy donors
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 05-Plotnikova.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/6653/1/05-Plotnikova.pdf
resources.format: Adobe PDF
resources.size: 482,13 kB