title: Non-natural 2H-azirine-2-carboxylic acids: an expedient synthesis and antimicrobial activity
metadata.name: dc.contributor.author
metadata.value: Sakharov, Pavel A.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Koronatov, Alexander N.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Khlebnikov, Alexander F.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Novikov, Mikhail S.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Glukharev, Artem G.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Rogacheva, Elizaveta V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Kraeva, Liudmila A.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Sharoyko, Vladimir V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Tennikova, Tatiana B.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Rostovskii, Nikolai V.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2019-11-28T13:16:04Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2019-11-28T13:16:04Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2019-11-21
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: RSC Adv., 2019, 9, 37901
metadata.lang: en_GB
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/16709
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: Non-natural 2H-azirine-2-carboxylic acids were obtained in high yields by FeCl2-catalyzed isomerization of
  5-chloroisoxazoles to azirine-2-carbonyl chlorides followed by their hydrolysis. The 3-aryl- and 3-
  heteroaryl-substituted acids are stable during prolonged storage, exhibit antibacterial activity against
  ESKAPE pathogens and show a low level of cytotoxicity
metadata.lang: en_GB
metadata.name: dc.description.sponsorship
metadata.value: the Scientifc Council of the President of the Russian Federation (MK-2698.2019.3)
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: en
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: The Royal Society of Chemistry
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: 10.1039/c9ra09345a;
metadata.lang: -
metadata.name: dc.title
metadata.value: Non-natural 2H-azirine-2-carboxylic acids: an expedient synthesis and antimicrobial activity
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: c9ra09345a.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/16709/1/c9ra09345a.pdf
resources.format: Adobe PDF
resources.size: 658,34 kB