title: Infrared spectroscopy of human serum albumin in the presence of metal ions
metadata.name: dc.contributor.author
metadata.value: Romanov, Nikolai M.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Andreeva, Maria V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Chikhirzhina, Elena V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Polyanichko, Alexander M.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2017-07-19T10:52:08Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2017-07-19T10:52:08Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2017-06
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Romanov N.M., AndreevaM. V., Chikhirzhina E. V., Polyanichko A.M. Infrared spectroscopy of human serum albumin in the presence of metal ions. Vestnik SPbSU. Physics and Chemistry. 2017, vol. 4 (62), issue 2, pp. 146–152.
metadata.lang: en_GB
metadata.name: dc.identifier.other
metadata.value: 10.21638/11701/spbu04.2017.204
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/6961
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: The interaction of human serum albumin (HSA) with divalent metal ions Ca2+ and Mn2+ was
  studied at various molar ratios [Me2+] : [HSA]. The interaction was studied by means of FTIR
  spectroscopy and protein heat denaturation in solution. Based on the analysis of the FTIR
  spectra we have shown that the interaction of HSA with Ca2+ and Mn2+ ions in solution leads
  to increase in the amount of β-sheet structures accompanied by decreasing α-helical content in
  the protein’s secondary structure. However, experiments of protein heat denaturation in solution
  has demonstrated that the mechanism of these changes is different for Ca2+ and Mn2+. Refs 15.
  Figs 4. Tables 2.
metadata.lang: en_GB
metadata.name: dc.description.sponsorship
metadata.value: Работа выполнена при финансовой поддержке Российского фонда фундаментальных исследований
  (гранты № 15-08-06876, 15-04-06993).
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: ru
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Vestnik of St Petersburg University. Physics and Chemistry;Volume 4 (62); Issue 2
metadata.lang: -
metadata.name: dc.subject
metadata.value: albumins
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: FTIR spectroscopy
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: secondary structure of proteins
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: metal ions
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Infrared spectroscopy of human serum albumin in the presence of metal ions
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 04-Romanov.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/6961/1/04-Romanov.pdf
resources.format: Adobe PDF
resources.size: 375,27 kB