title: Creatine kinase in periprocedural myocardial injury after percutaneous coronary intervention
metadata.name: dc.contributor.author
metadata.value: Vorobyova, Anastasya V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Bart, Victor A.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Bondarenko, Boris B.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Dorofeykov, Vladimir V.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Kalinin, Oleg M.
metadata.lang: -
metadata.name: dc.contributor.author
metadata.value: Kuleshova, Elvira V.
metadata.lang: -
metadata.name: dc.date.accessioned
metadata.value: 2017-07-04T14:33:16Z
metadata.lang: -
metadata.name: dc.date.available
metadata.value: 2017-07-04T14:33:16Z
metadata.lang: -
metadata.name: dc.date.issued
metadata.value: 2017-03
metadata.lang: -
metadata.name: dc.identifier.citation
metadata.value: Vorobyova A. V., Bart V. A., Bondarenko B. B., Dorofeykov V. V., Kalinin O. M., Kuleshova E. V. Creatine kinase in periprocedural myocardial injury after percutaneous coronary intervention. Vestnik SPbSU. Medicine, 2017, vol. 12, issue 1, pp. 4–17.
metadata.lang: en_GB
metadata.name: dc.identifier.other
metadata.value: 10.21638/11701/spbu11.2017.101
metadata.lang: -
metadata.name: dc.identifier.uri
metadata.value: http://hdl.handle.net/11701/6640
metadata.lang: -
metadata.name: dc.description.abstract
metadata.value: Patients with ischemic heart disease undergoing percutaneous coronary intervention are
  characterized by various degrees of myocardial damage. The purpose of the study is to investigate the
  dependence of micro-injuries of the myocardium on the nature of the damage to the coronary arteries
  and the features of the procedure during the interventional treatment in patients with stable angina.
  Myocardial damage was diagnosed based on the dynamics of cardiospecific biomarkers of creatine
  kinase-myocardial band isoenzyme before and 24 hours after intervention.
  Providing the analysis of the phenomenon in the totality of its characteristics, the use of
  multivariate statistics (principal component method, stepwise discriminant analysis) allowed not
  only to differentiate patients with or without periprocedural myocardial damage and to determine
  the possibility of their differentiation by the impacts of such characteristics as “the total number of
  inflations” and “total number of affected arteries”, but also to point out a level of creatine kinase before
  intervention as a sign of potential vulnerability/resistance of myocardium.
  The latter can be considered as a separate component characterizing the state of cardiomyocytes
  and the degree of risk of postprocedural myocardial damage. Thus, investigation of nature of the
  complication is important not only for its prevention but for study the whole cardioprotection issue.
  Refs 26. Figs 2. Tables 7.
metadata.lang: en_GB
metadata.name: dc.language.iso
metadata.value: en
metadata.lang: en_GB
metadata.name: dc.publisher
metadata.value: St Petersburg State University
metadata.lang: en_GB
metadata.name: dc.relation.ispartofseries
metadata.value: Vestnik of St Petersburg University. Medicine;Volume 12; Issue 1
metadata.lang: -
metadata.name: dc.subject
metadata.value: myocardial damage
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: creatine phosphokinase
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: principal components
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: stepwise discriminant analysis
metadata.lang: en_GB
metadata.name: dc.subject
metadata.value: cardioprotection
metadata.lang: en_GB
metadata.name: dc.title
metadata.value: Creatine kinase in periprocedural myocardial injury after percutaneous coronary intervention
metadata.lang: en_GB
metadata.name: dc.type
metadata.value: Article
metadata.lang: en_GB
resources.filename: 01-Vorobyova.pdf
resources.url: https://dspace.spbu.ru/bitstream/11701/6640/1/01-Vorobyova.pdf
resources.format: Adobe PDF
resources.size: 704,82 kB